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蔡晴

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蔡晴 教授

 简历


博士、教授、博士生导师
生物材料系 副主任
办公室: 科技大厦817
电子邮件:caiqing@mail.buct.edu.cn
 

教育背景

 
1989.9-1993.7 武汉大学,学士
1997.9-2000.7 中国科学院化学研究所,硕士
2000.9-2003.7 中国科学院化学研究所,博士
 

工作经历

 
1993.7-1997.8 北京玻璃钢研究设计院 助理工程师
2013.1-2014.1 宾夕法尼亚州立大学 访问学者
2003.9-至今 北京化工大学材料科学与工程学院 讲师、副教授、教授

研究领域

 

主要致力于新型生物材料、组织工程支架材料、药物控制释放载体材料及植入材料的研究。侧重于合成生物可降解高分子的合成与改性,及其天然高分子和无机材料的复合,在仿生天然细胞外基质结构和组成的指导思想下,着重研发口腔/硬组织再生修复材料。

 


研究成果及荣誉

 

2015年:蔡晴(1/6, 口腔硬组织修复高分子基生物医用材料及临床应用,中国石油和化学工业联合会科学进步奖,二等奖

2014年:蔡晴(6/8),生物降解高分子材料多层次微结构的调控及其生物医学功能构筑,国家教育部,自然科学奖,一等奖

2013年:蔡晴(5/6),多尺度、多维度填料协同增强树脂基口腔生物材料及临床修复技术,国家教育部,技术发明奖,二等奖

2011年:教育部“新世纪优秀人才支持计划”

2003年:中国科学院院长优秀奖


目前发表SCI收录论文60余篇,被引用740余次,h因子为15。申请专利19项,获授权12项。

近期发表的部分论文及著作

 

【文章】

1.Zhiwei Ren, Shiqing Ma, Le Jin, Zihao Liu, Deping Liu, Xu Zhang, Qing Cai*, Xiaoping Yang*, Repairing bone defect with three-dimensional cellular construct composed of multi-layered cell sheet on electrospun mesh, Biofabrication, 2017, 9: 025036.

2. Zhaohui Huang, Pengfei Wei, Le Jin, Xiaoqing Hu, Qing Cai*, Xiaoping Yang*, Photoluminescent polyphosphazene nanoparticles for in situ simvastatin delivery to improve osteocompatibility of BMSCs, J Mater Chem B,, 5: 9300-9311.

3. Siqi Zhu, Wei Jing, Xiaoqing Hu, Zirong Huang, Qing Cai*, Yingfang Ao, Xiaoping Yang*, Time-dependent effect of electrical stimulation on osteogenic differentiaon of bone mesenchymal stromal cells cultured on conductive nanofibers, J Biomed Mater Res A, 2017, 105: 3369-3383.

4. Zhaohui Huang, Lika Yang, Xuehuii Zhang, Bingyuan Ruan, Xiaoqing Hu, Xuliang Deng, Qing Cai*, Xiaoping Yang, Photoluminescent biodegradable polyphosphazenes for long-term in vivo tracking for tissue engineering application, Macromolecules, 2016, 49: 8508-8519.

5. Caijin Zhang, Man Cao, Jinle Lan, Pengfei Wei, Qing Cai*, Xiaoping Yang, Regulating proliferation and differentiation of osteoblasts on poly(l-lactide)/gelatin composite nanofibers via timed biomineralization, J Biomed Mater Res A, 2016, 104: 1968-1980.

6. Xiurui Zhang, Xiaoqing Hu, Xiaolong Jia, Lika Yang, Qingyang Meng, Yuanyuan Shi, Zhengzheng Zhang, Qing Cai*, Yingfang Ao*, Xiaoping Yang, Cell studies of hybridized carbon nanofibers containing bioactive glass nanoparticles using bone mesenchymal stromal cells, Sci Rep, 2016, 6: 38685.

7. Zhiwei Ren, Yang Wang, Shiqing Ma, Shun Duan, Xiaoping Yang, Ping Gao, Xu Zhang*, Qing Cai*, Effective bone regeneration using thermo-sensitive poly(N-isopropylacrylamide) grafted gelatin as injectable carrier for bone mesenchymal stem cells, ACS Appl Mater Interface, 2015, 7: 19006-19015.

8. Ying Wang, Yan Wei, Xuehui Zhang, Mingming Xu, Feng Liu, Qi Ma, Qing Cai*, Xuliang Deng*, PLGA/PDLLA core–shell submicron spheres sequential release system: Preparation, characterization and promotion of bone regeneration in vitro and in vivo, Chem Eng J, 2015, 273: 490-501

9. Yougang Guo, Jinle Lan, Caijin Zhang, Man Cao, Qing Cai*, Xiaoping Yang, Mineralization on polylactide/gelatin composite nanofibers using simulated body fluid containing amino acid, Appl Surf Sci, 2015, 349: 538~548.

10. Pei Zhao, Dawei Li, Fei Yang*, Yuanzheng Ma, Tiantian Wang, Shun Duan, Hong Shen, Qing Cai*, Decheng Wu, Xiaoping Yang, Shenguo Wang, In vitro and in vivo drug release behavior and osteogenic potential of a composite scaffold based on poly (ε-caprolactone)-block-poly (lactic-co-glycolic acid) and beta-tricalcium phosphate, J Mater Chem B, 2015, 3: 6885-6896.

11. XL Li, JL Lan, M Ai, YG Guo, Q Cai*, Xiaoping Yang. Biomineralization on polymer-coated carbon nanotubes with different surface functional groups. Colloids Surf B Biointerfaces 2014, 123: 753-761.

12. DY Shan, Y Li, YC Zhao, XP Yang, Q Cai*. Improve miscibility of biodegradable polyester/polyphosphazene blends by using cross-linkable polyphosphazene. Biomed Mater 2014, 9(6): 061001.

13. XL Jia, TH Tang, D Cheng, LJ Guo, CH Zhang, R Zhang, Q Cai*, XP Yang. Growth mechanism of bioglass nanoparticles in polyacrylonitrile-based carbon nanofibers. RSC Adv 2014, 4: 64299-64309.

14. Y Li, YZ Shi, S Duan, DY Shan, Q Cai*, XP Yang. Electrospun biodegradable polyorganophosphazene fibrous matrix with poly(dopamine) coating for bone regeneration. J Biomed Mater Res A 2014, 102: 3894–3902.

15. LY Cheng, XG Zhou, H Zhong, Q Cai*, XP Yang. NaF-loaded core-shell nanofibers as reinforcements for dental restorative resins. Mater Sci Eng C Mater 2014, 34: 262-269.

16. YC Zhao, JL Lan, XY Wang, XL Deng, Q Cai*, XP Yang. Radiopaque dental composite resin containing iodine-substituted cyclophosphazenes. Mater Sci Eng C Mater 2014, 43: 432-438.

17. Q Cai, JF Mao, XL Li, XP Yang*. Macroporous and nanofibrous PLLA scaffold reinforced with biomimetic CaP-coated multiwalled carbon nanotubes. Mater Lett 2014, 128: 238-241.

18. Q Yang, G Sui, YZ Shi, S Duan, JQ Bao, Q Cai*, XP Yang. Osteocompatibility characterization of polyacrylonitrile carbon nanofibers decorated with bioactive glass nanoparticles. Carbon 2013, 56: 288-295.

19. S Duan, XP Yang, JF Mao, B Qi, Q Cai*, H Shen, F Yang*, XL Deng, SG Wang. Osteocompatibility evaluation of poly(glycine ethyl ester-co-alanine ethyl ester)phosphazene with honeycomb-patterned surface topography. J Biomed Mater Res 2013, 101A: 307-317.

20. Y Li, Q Chen, M Yi, XG Zhou, XZ Wang, Q Cai*, XP Yang. Effect of surface modification of fiber post using dopamine polymerization on interfacial adhesion with core resin. Appl Surf Sci 2013, 274: 248-254.

【专利】

一种可注射聚膦腈/明胶复合水凝胶及其制备方法, ZL 201110109276.X

引导组织再生膜及其制备方法, ZL 201110006820.8

齿科修复用一体化纤维桩及其制备方法, ZL201010124736.1

仿生磷酸钙复合纤维支架材料及制备方法, ZL200910078991.4

【著作】

[1] Q. Cai, K. Subramani, R.T. Mathew, X.P. Yang. Carbon nanomaterials for implant dentistry and bone tissue engineering, Chapter 18 in <Nanobiomaterials in Clinical Dentistry>, edited by K. Subramani, W. Ahmed and J.K. Hartsfield, Published by Elsevier Inc., 2013, PP.359-388.

[2] Q. Cai, X.P. Yang, Multiwalled carbon nanotubes/hydroxyapatite nanoparticles incorporated GTR membranes, Chapter 10 in <Emerging nanotechnologies in Dentistry>, edited by K. Subramani and W. Ahmed, Published by Elsevier Inc., 2012, PP.151-170.

[3] 蔡晴,杨小平. 参编《有机纳米功能材料——高压静电纺丝技术与纳米纤维》第3章和第5章,王策、卢晓峰主 编,科学出版社,2011-7出版